Intended Use: TB-500 is designed for Research Purposes only.

Storage: Store the vial in a cool, dry place away from direct sunlight. Once reconstituted, keep refrigerated at 2-8°C.

Solubility: Reconstitute with bacteriostatic water for best results.

Shelf Life: The lyophilized form has a shelf life of 24 months when properly stored. Once reconstituted, refrigerate and use within 4-6 weeks.

Handling: Ensure sterile techniques are used to maintain the product’s integrity during research.

Study on Accelerated Healing

TB-500 speeds up healing.Research shows that TB-500 can accelerate the healing of various injuries, including muscle strains and ligament injuries. It promotes cell migration and tissue repair, reducing recovery time significantly.

Study on Muscle and Tissue Repair

TB-500 aids muscle and tissue repair.Studies indicate that TB-500 supports muscle and tissue repair, making it popular among athletes. It helps recover from strenuous workouts and reduces the risk of overuse injuries.

Study on Joint Health

TB-500 improves joint health.Research suggests that TB-500 can promote tissue repair in joints and connective tissues. This makes it a potential treatment for conditions like osteoarthritis and tendonitis.

Study on Cardiovascular Support

TB-500 supports cardiovascular health.Some studies have found that TB-500 can promote the growth of new blood vessels, which is beneficial for cardiovascular health. This could help individuals with heart conditions or those recovering from cardiac injuries.

Study on Anti-Inflammatory Effects

TB-500 reduces inflammation.Research shows that TB-500 has strong anti-inflammatory properties. It helps reduce swelling and pain, facilitating a smoother and faster recovery process.

Study on Neurological Benefits

TB-500 may aid in brain recovery.Studies on rats suggest that TB-500 can promote blood vessel and neuronal development in the brain, potentially aiding recovery from strokes and improving cognitive functions.

Study on Eye Health

TB-500 improves eye health.A study found that TB-500 eye drops significantly improved symptoms of severe dry eye disease. Patients experienced reduced ocular discomfort and better corneal health.

Study on Wound Healing

TB-500 enhances wound healing.Research indicates that TB-500 can significantly improve wound healing by promoting angiogenesis, the formation of new blood vessels, which is crucial for tissue repair.

Mechanisms of Action for TB-500 (Thymosin Beta-4)

TB-500, the synthetic form of the naturally occurring peptide Thymosin Beta-4, is widely researched for its healing properties. It has been used in various medical fields to enhance tissue repair and decrease recovery time from injuries. TB-500's mechanisms of action include modulation of actin, promotion of cell growth, migration, and proliferation, as well as anti-inflammatory properties.

Enhancement of Actin Dynamics

One of the primary mechanisms of TB-500 is its role in actin regulation. Actin is a vital component of the cellular cytoskeleton, and its polymerization and depolymerization are crucial for cell movement and morphology. TB-500 binds to actin in a manner that promotes actin filament assembly and stabilizes the existing filaments, enhancing cell mobility and proliferation necessary for healing.

Promotion of Cell Growth and Migration

TB-500 significantly influences cell migration and growth, which are essential for tissue repair. By facilitating the movement of cells to sites of injury and supporting their proliferation, TB-500 accelerates the healing process, particularly in connective tissues like muscle, skin, and ligaments.

Angiogenic Effects

The peptide also exhibits angiogenic effects, meaning it can induce the growth of new blood vessels from existing ones. This is particularly beneficial in wound healing as it ensures an adequate blood supply, which is critical for delivering oxygen and nutrients necessary for repair processes.

Anti-inflammatory Properties

TB-500 has been shown to possess strong anti-inflammatory properties. It helps modulate cytokine and protein expression involved in inflammatory responses, reducing inflammation and facilitating a quicker recovery from injuries.

Tissue Protection

Apart from promoting healing, TB-500 helps protect and regenerate tissues. It can encourage the differentiation of stem cells into various cell types needed for repair, and it helps protect cells from oxidative stress, which can damage DNA and other cellular structures.

Versatility in Medical Applications

Due to its potent healing capabilities, TB-500 is used in a variety of medical applications, from aiding athletes in recovery from muscle injuries to enhancing the treatment outcomes in chronic wounds and heart conditions. Its ability to improve flexibility, reduce joint inflammation, and increase hair growth also make it a promising compound in broader therapeutic contexts.

Overall, TB-500 is a powerful therapeutic agent that leverages cellular processes to accelerate healing, reduce inflammation, and improve functional recovery across a range of medical conditions.