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  • Enhances muscle growth and repair
  • Longer acting than regular IGF-1
  • Used in research and bodybuilding

IGF-1 LR3 is a modified form of insulin-like growth factor-1, featuring an extended half-life which allows it to act longer in the body. This makes it a popular choice among bodybuilders for its potential to promote muscle growth and enhance recovery.

Legal Notice: This item is available exclusively for scientific research purposes. It is sold in a lyophilized (freeze-dried) state, contained within a hermetically sealed and sterile vial. Use requires extra equipment such as bacteriostatic water for reconstitution, syringes and needles for extraction, and alcohol swabs to sanitize vial caps. The cap color, may differ from the images shown. Learn More

Benefits and Applications

IGF-1 LR3 offers several benefits, particularly in the contexts of bodybuilding:

  • Promotes accelerated muscle growth and recovery
  • Enhances cell repair and regeneration
  • May improve muscle retention during aging
  • Supports increased protein synthesis
  • Potentially reduces body fat
  • Used in research for its extended activity compared to natural IGF-1

These attributes make it a valuable tool for those looking to enhance physical performance and for scientists studying growth factors.

Research and Studies

  1. Myostatin Inhibition Study:
  • Participants: The study was conducted on animal models, specifically mice with Duchenne muscular dystrophy (DMD).
  • Methodology: Researchers explored the potential of IGF-1 LR3 to counteract the effects of myostatin, a protein that inhibits muscle growth. This was part of an investigation into muscle preservation and enhancement in conditions that lead to muscle degeneration.
  • Results: The results indicated that IGF-1 LR3 effectively inhibited myostatin, which helped in preserving muscle cells and potentially delaying muscle degradation, suggesting its utility in treating muscle-wasting conditions like DMD.
  1. Study on Glucocorticoid Signaling:
  • Participants: This research was speculative and largely theoretical, extrapolating from existing studies on various animal models, including cows and pigs, and considering potential applications in human health.
  • Methodology: The study assessed the role of IGF-1 LR3 in mitigating the adverse effects of glucocorticoids, which are used to treat inflammation but can cause significant side effects like muscle atrophy and bone density loss.
  • Results: The hypothesis was that IGF-1 LR3 could enhance the therapeutic effects of glucocorticoids while reducing their negative impacts on muscle and bone tissues. This could potentially make IGF-1 LR3 a valuable adjunct therapy in the management of chronic inflammatory conditions.

These studies are primarily foundational and exploratory, highlighting the therapeutic potential of IGF-1 LR3 in areas beyond just muscle growth, such as in the treatment of chronic diseases and conditions involving muscle and bone degradation.

Mechanism of Action

IGF-1 LR3, a modified version of insulin-like growth factor-1, acts by binding to IGF-1 receptors, enhancing cell proliferation and preventing apoptosis. It promotes muscle and tissue growth by increasing protein synthesis and reducing protein degradation. This peptide variant has an extended half-life compared to natural IGF-1, allowing for prolonged biological activity, which is crucial for its effectiveness in muscle growth and recovery.

Safety and Side Effects

The safety profile of IGF-1 LR3 includes risks such as hypoglycemia and potential organ enlargement. Proper dosage management and medical oversight are crucial to minimize these risks, highlighting the importance of careful monitoring when using this peptide.

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